Medical Engineering & Physics
Volume 34, Issue 1 , Pages 2-8 , January 2012

Effects of glucocorticoid on BMD, micro-architecture and biomechanics of cancellous and cortical bone mass in OVX rabbits

  • Xuli Liu

      Affiliations

    • Department of Orthopaedics, Xijing Hospital, the Fourth Military Medical University, 15 Changle West Road, Xi’an 710032, Shaanxi, China
    • ,
  • Wei Lei

      Affiliations

    • Department of Orthopaedics, Xijing Hospital, the Fourth Military Medical University, 15 Changle West Road, Xi’an 710032, Shaanxi, China
    • Corresponding Author InformationCorresponding author. Tel.: +86 029 84771011; fax: +86 029 84771011.
    • ,
  • Zixiang Wu

      Affiliations

    • Department of Orthopaedics, Xijing Hospital, the Fourth Military Medical University, 15 Changle West Road, Xi’an 710032, Shaanxi, China
    • ,
  • Yi Cui

      Affiliations

    • Department of Orthopaedics, Xijing Hospital, the Fourth Military Medical University, 15 Changle West Road, Xi’an 710032, Shaanxi, China
    • ,
  • Baojun Han

      Affiliations

    • Department of Orthopaedics, Xijing Hospital, the Fourth Military Medical University, 15 Changle West Road, Xi’an 710032, Shaanxi, China
    • ,
  • Suochao Fu

      Affiliations

    • Department of Orthopaedics, Xijing Hospital, the Fourth Military Medical University, 15 Changle West Road, Xi’an 710032, Shaanxi, China
    • ,
  • Changli Jiang

      Affiliations

    • Clinical Lab, Kunming General Hospital of Chengdu Military Area Command of Chinese PLA, Daguan Roast, Kunming, Yunnan 650032, China

Received 10 December 2010 ,Revised 12 May 2011 ,Accepted 18 June 2011.

  • Image Result

    Dual-energy X-ray absorptiometry measurement. Left: L3, L4 and L5. Right: Femoral midshaft (8mm×12mm ROI) and femoral condyle (7mm×7mm ROI).

    Dual-energy X-ray absorptiometry measurement. Left: L3, L4 and L5. Right: Femoral midshaft (8mm×12mm ROI) and femoral condyle (7mm×7mm ROI).

  • Image Result

    The right femoral condyle used for micro-CT measurement.

    The right femoral condyle used for micro-CT measurement.

  • Image Result

    The method of analyzing cortical bone with micro-CT. Left: The transverse plane of cortical bone. Right: The axial plane of cortical bone.

    The method of analyzing cortical bone with micro-CT. Left: The transverse plane of cortical bone. Right: The axial plane of cortical bone.

  • Image Result

    Biomechanical tests for bone specimens. Left: Uniaxial compression test for vertebrae. Right: Three-point bending test for femoral diaphysis.

    Biomechanical tests for bone specimens. Left: Uniaxial compression test for vertebrae. Right: Three-point bending test for femoral diaphysis.

  • Image Result

    Three-dimensional trabecular micro-architectural images of rabbit vertebral body. From left to right were sham, OVX and OVX-GC group, respectively.

    Three-dimensional trabecular micro-architectural images of rabbit vertebral body. From left to right were sham, OVX and OVX-GC group, respectively.

  • Image Result

    Three-dimensional trabecular micro-architectural images of rabbit femoral condyle. From left to right were sham, OVX and OVX-GC group, respectively.

    Three-dimensional trabecular micro-architectural images of rabbit femoral condyle. From left to right were sham, OVX and OVX-GC group, respectively.

  • Image Result

    Two-dimensional trabecular micro-architectural images of rabbit femoral condyle. From left to right were sham, OVX and OVX-GC group, respectively.

    Two-dimensional trabecular micro-architectural images of rabbit femoral condyle. From left to right were sham, OVX and OVX-GC group, respectively.

PII: S1350-4533(11)00147-0

doi: 10.1016/j.medengphy.2011.06.010

Medical Engineering & Physics
Volume 34, Issue 1 , Pages 2-8 , January 2012

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