Medical Engineering & Physics
Volume 32, Issue 4 , Pages 304-311, May 2010

Development of tissue adhesion method using integrated low-level energies

  • Ayako Katoh

      Affiliations

    • Ibaraki University, 1-12-1 Nakanarusawa, Hitachi, Ibaraki, Japan
    • ,
  • Toru Masuzawa

      Affiliations

    • Ibaraki University, 1-12-1 Nakanarusawa, Hitachi, Ibaraki, Japan
    • Corresponding Author InformationCorresponding author. Tel.: +81 294 38 5250.
    • ,
  • Kazuhide Ozeki

      Affiliations

    • Ibaraki University, 1-12-1 Nakanarusawa, Hitachi, Ibaraki, Japan
    • ,
  • Akio Kishida

      Affiliations

    • Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo, Japan
    • ,
  • Tsuyoshi Kimura

      Affiliations

    • Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo, Japan
    • ,
  • Tetsuya Higami

      Affiliations

    • Sapporo Medical University, S1W17, Chuo-ku, Sapporo, Japan

Received 2 March 2009; received in revised form 19 December 2009; accepted 23 December 2009. published online 18 January 2010.

Abstract 

We have developed a method that allows biological tissues to be adhered together with minimal invasion by delivering integrated low-level energies from heat, pressure, and vibration. Tensile tests on adhered slices of porcine aorta were performed to determine the relationships between adhesive strength and conditions such as adhesion temperature, time, pressure, and vibration. The maximal adhesive shear tensile strength using the proposed method was 0.2MPa, which is half the strength of the porcine aorta and stronger than surgical tissue adhesive. Adhesion strength increased in proportion to temperature, time, and pressure, and also in the presence of vibration, indicating that vibrational energy contributes to the adhesive mechanism and strength. Adhesive stability, the effect of heat on adhesive strength, and the ability of tissue to adhere to artificial materials were also clarified.

Keywords: Angiorrhaphy, Vessel sealing, Adhesive grafts, Thermal transfer

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.
 

PII: S1350-4533(09)00266-5

doi:10.1016/j.medengphy.2009.12.005

Medical Engineering & Physics
Volume 32, Issue 4 , Pages 304-311, May 2010

Article Tools

* Image Usage & Resolution