Medical Engineering & Physics
Volume 30, Issue 10 , Pages 1318-1337 , December 2008

Rheological properties of the tissues of the central nervous system: A review

  • Shaokoon Cheng

      Affiliations

    • Both these authors have contributed equally to this work.
    • ,
  • Elizabeth C. Clarke

      Affiliations

    • Both these authors have contributed equally to this work.
    • ,
  • Lynne E. Bilston

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: +61 2 9399 1073; fax: +61 2 9399 1082.

Received 11 March 2008 ,Revised 23 May 2008 ,Accepted 1 June 2008.

References 

  1. Holbourn A. Mechanics of head injuries. Lancet. 1943;2:1057–1065
  2. Arbogast KB, Thibault KL, Pinheiro BS, Winey KI, Margulies SS. A high-frequency shear device for testing soft biological tissues. J Biomech. 1997;30(7):757–759
  3. Fallenstein GT, Hulce VD, Melvin JW. Dynamic mechanical properties of human brain tissue. J Biomech. 1969;2(3):217–226
  4. Bilston LE, Liu Z, Phan-Thien N. Large strain behaviour of brain tissue in shear: some experimental data and differential constitutive model. Biorheology. 2001;38(4):335–345
  5. Shuck L, Advani S. Rheological response of human brain tissue in shear. J Basic Eng. 1972;905–911
  6. Hrapko M, van Dommelen JA, Peters GW, Wismans JS. The mechanical behaviour of brain tissue: large strain response and constitutive modelling. Biorheology. 2006;43(5):623–636
  7. Brands DW, Bovendeerd PH, Peters GW, Wismans JS. The large shear strain dynamic behaviour of in-vitro porcine brain tissue and a silicone gel model material. Stapp Car Crash J. 2000;44:249–260
  8. Nicolle S, Lounis M, Willinger R, Palierne JF. Shear linear behavior of brain tissue over a large frequency range. Biorheology. 2005;42(3):209–223
  9. Peters GW, Meulman JH, Sauren AA. The applicability of the time/temperature superposition principle to brain tissue. Biorheology. 1997;34(2):127–138
  10. Cheng S, Bilston LE. Unconfined compression of white matter. J Biomech. 2007;40(1):117–124
  11. Galford JE, McElhaney JH. A viscoelastic study of scalp, brain, and dura. J Biomech. 1970;3(2):211–221
  12. Estes M, McElhaney J. Response of brain tissue of compressive loading. In: Proceedings of the 4th ASME biomechanics conference. 1970;p. 70BHF13
  13. Suh JK, Spilker RL. Indentation analysis of biphasic articular cartilage: nonlinear phenomena under finite deformation. J Biomech Eng. 1994;116(1):1–9
  14. Warner MD, Taylor WR, Clift SE. Finite element biphasic indentation of cartilage: a comparison of experimental indenter and physiological contact geometries. Proc Inst Mech Eng [H]. 2001;215(5):487–496
  15. Gefen A, Margulies SS. Are in vivo and in situ brain tissues mechanically similar?. J Biomech. 2004;37(9):1339–1352
  16. Miller K. Method of testing very soft biological tissues in compression. J Biomech. 2005;38(1):153–158
  17. Walsh EK, Schettini A. Calculation of brain elastic parameters in vivo. Am J Physiol. 1984;247:R693–R700
  18. Hung TK, Lin HS, Bunegin L, Albin MS. Mechanical and neurological response of cat spinal cord under static loading. Surg Neurol. 1982;17(3):213–217
  19. Carlson GD, Warden KE, Barbeau JM, Bahniuk E, Kutina-Nelson KL, Biro CL, et al. Viscoelastic relaxation and regional blood flow response to spinal cord compression and decompression. Spine. 1997;22(12):1285–1291
  20. Kwon BK, Oxland TR, Wolfram T. Animal models used in spinal cord regeneration research. Spine. 2002;27(14):1504–1510
  21. Miller K, Chinzei K. Mechanical properties of brain tissue in tension. J Biomech. 2002;35(4):483–490
  22. Velardi F, Fraternali F, Angelillo M. Anisotropic constitutive equations and experimental tensile behavior of brain tissue. Biomech Model Mechanobiol. 2006;5(1):53–61
  23. Chang GL, Hung TK, Bleyaert A, Jannetta PJ. Stress–strain measurement of the spinal cord of puppies and their neurological evaluation. J Trauma. 1981;21(9):807–810
  24. Chang GL, Hung TK, Feng WW. An in-vivo measurement and analysis of viscoelastic properties of the spinal cord of cats. J Biomech Eng. 1988;110(2):115–122
  25. Hung TK, Chang GL. Biomechanical and neurological response of the spinal cord of a puppy to uniaxial tension. J Biomech Eng. 1981;103(1):43–47
  26. Hung TK, Chang GL, Chang JL, Albin MS. Stress–strain relationship and neurological sequelae of uniaxial elongation of the spinal cord of cats. Surg Neurol. 1981;15(6):471–476
  27. Hung TK, Chang GL, Lin HS, Walter FR, Bunegin L. Stress–strain relationship of the spinal cord of anesthetized cats. J Biomech. 1981;14(4):269–276
  28. Fiford RJ, Bilston LE. The mechanical properties of rat spinal cord in vitro. J Biomech. 2005;38(7):1509–1515
  29. Oakland RJ, Hall RM, Wilcox RK, Barton DC. The biomechanical response of spinal cord tissue to uniaxial loading. Proc Inst Mech Eng [H]. 2006;220(4):489–492
  30. Bilston LE, Thibault LE. The mechanical properties of the human cervical spinal cord in vitro. Ann Biomed Eng. 1996;24(1):67–74
  31. Sahay KB, Mehrotra R, Sachdeva U, Banerji AK. Elastomechanical characterization of brain tissues. J Biomech. 1992;25(3):319–326
  32. Sklar FH, Beyer CW, Clark WK. Physiological features of the pressure–volume function of brain elasticity in man. J Neurosurg. 1980;53(2):166–172
  33. Sklar FH, Diehl JT, Beyer CW, Clark WK. Brain elasticity changes with ventriculomegaly. J Neurosurg. 1980;53(2):173–179
  34. Lippert SA, Rang EM, Grimm MJ. The high frequency properties of brain tissue. Biorheology. 2004;41(6):681–691
  35. Muthupillai R, Ehman RL. Magnetic resonance elastography. Nat Med. 1996;2(5):601–603
  36. Green M, Bilston L, Sinkus R. In vivo brain viscoelastic properties measured by magnetic resonance elastography. NMR Biomed. 2008;21:755–764
  37. Hamhaber U, Sack I, Papazoglou S, Rump J, Klatt D, Braun J. Three-dimensional analysis of shear wave propagation observed by in vivo magnetic resonance elastography of the brain. Acta Biomater. 2007;3(1):127–137
  38. Garo A, Hrapko M, van Dommelen JA, Peters GW. Towards a reliable characterisation of the mechanical behaviour of brain tissue: the effects of post-mortem time and sample preparation. Biorheology. 2007;44(1):51–58
  39. Arbogast KB, Margulies SS. Regional differences in mechanical properties of porcine central nervous system. In: Proceedings of the 41st stapp car crash conference. 1997;p. 293–300
  40. Nicolle S, Lounis M, Willinger R. Shear properties of brain tissue over a frequency range relevant for automotive impact situations: new experimental results. Stapp Car Crash J. 2004;48:239–258
  41. Donnelly BR, Medige J. Shear properties of human brain tissue. J Biomech Eng. 1997;119(4):423–432
  42. Prange MT, Margulies SS. Regional, directional, and age-dependent properties of the brain undergoing large deformation. J Biomech Eng. 2002;124(2):244–252
  43. Arbogast KB, Margulies SS. Material characterization of the brainstem from oscillatory shear tests. J Biomech. 1998;31(9):801–807
  44. Thibault KL, Margulies SS. Age-dependent material properties of the porcine cerebrum: effect on pediatric inertial head injury criteria. J Biomech. 1998;31(12):1119–1126
  45. Gefen A, Gefen N, Zhu Q, Raghupathi R, Margulies SS. Age-dependent changes in material properties of the brain and braincase of the rat. J Neurotrauma. 2003;20(11):1163–1177
  46. Bilston L, Liu Z, Phan-Thien N. Linear viscoelastic properties of bovine brain tissue in shear. Biorheology. 1997;34:377–385
  47. Macosko CW. Rheology: principles, measurements and applications. New York: Wiley & Sons; 1994;
  48. Wu J, Dong R, Schopper A. Analysis of effects of friction on the deformation behavior of soft tissues in unconfined compression tests. J Biomech. 2004;37:147–155
  49. Nasseri S, Bilston L, Tanner R. Lubricated squeezing flow: a useful method for measuring the viscoelastic properties of soft tissues. Biorheology. 2003;40(5):545–551
  50. Miller K, Chinzei K. Constitutive modelling of brain tissue: experiment and theory. J Biomech. 1997;30(11/12):1115–1121
  51. Koeneman J. Viscoelastic properties of brain tissue. Cleveland: Case Institute of Technology; 1966;
  52. Hirakawa K, Hashizume K, Hayashi T. Viscoelastic properties of human brain—for the analysis of impact injury. No To Shinkei. 1981;33(10):1057–1065
  53. Brands D, Bovendeerd PH, Peters GW, Wismans JS, Paas M, van Bree J. Comparison of the dynamic behaviour of brain tissue and two model materials. In: Proceedings of the 43rd Stapp Car Crash Conference. 1999;p. 313–320
  54. Takhounts EG, Crandall JR, Darvish K. On the importance of nonlinearity of brain tissue under large deformations. Stapp Car Crash J. 2003;47:79–92
  55. Tamura A, Hayashi S, Watanabe I, Nagayama K, Matsumoto T. Mechanical characterisation of brain tissue in high-rate compression. J Biomech Sci Eng. 2007;2(3):115–126
  56. Tunturi AR. Elasticity of the spinal cord, pia, and denticulate ligament in the dog. J Neurosurg. 1978;48(6):975–979
  57. Ozawa H, Matsumoto T, Ohashi T, Sato M, Kokubun S. Comparison of spinal cord gray matter and white matter softness: measurement by pipette aspiration method. J Neurosurg. 2001;95(Suppl. 2):221–224
  58. Ichihara K, Taguchi T, Shimada Y, Sakuramoto I, Kawano S, Kawai S. Gray matter of the bovine cervical spinal cord is mechanically more rigid and fragile than the white matter. J Neurotrauma. 2001;18(3):361–367
  59. Tunturi AR. Viscoelasticity of dog spinal cord. Physiol Chem Phys. 1980;12(4):373–378
  60. Shen F, Tay TE, Li JZ, Nigen S, Lee PV, Chan HK. Modified Bilston nonlinear viscoelastic model for finite element head injury studies. J Biomech Eng. 2006;128(5):797–801
  61. Arbogast K, Meaney D, Thibault L. Biomechanical characterization of the constitutive relationship for the brainstem. Proc Soc Automotive Eng. 1995;153–159
  62. Weaver JB, Perrinez PR, Bergeron JA, Kennedy FE, Wang H, Scott Lollis S, et al. The effects of interstitial tissue pressure on the measured shear modulus in vivo. Proc SPIE. 2007;6511

PII: S1350-4533(08)00105-7

doi: 10.1016/j.medengphy.2008.06.003

Medical Engineering & Physics
Volume 30, Issue 10 , Pages 1318-1337 , December 2008

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