Medical Engineering & Physics
Volume 30, Issue 7 , Pages 809-816 , September 2008

Doppler derived quantitative flow estimate in coronary artery bypass graft: A computational multiscale model for the evaluation of the current clinical procedure

  • Raffaele Ponzini

      Affiliations

    • Department of Bioengineering, Politecnico di Milano, Milan, Italy
    • Consorzio Interuniversitario Lombardo per l’Elaborazione e l’Automazione (CILEA), Milan, Italy
    • Corresponding Author InformationCorresponding author at: Via Raffaello Sanzio 4, 20090 Segrate (MI), Italy. Tel.: +39 02 26995390; fax: +39 02 2135520.
    • ,
  • Massimo Lemma

      Affiliations

    • CardioLab, Foundation for Research in Cardiac Surgery, Milan, Italy
    • ,
  • Umberto Morbiducci

      Affiliations

    • Department of Mechanics, Politecnico di Torino, Turin, Italy
    • ,
  • Franco M. Montevecchi

      Affiliations

    • Department of Mechanics, Politecnico di Torino, Turin, Italy
    • ,
  • Alberto Redaelli

      Affiliations

    • Department of Bioengineering, Politecnico di Milano, Milan, Italy
    • CardioLab, Foundation for Research in Cardiac Surgery, Milan, Italy

Received 23 April 2007 ,Revised 12 September 2007 ,Accepted 16 September 2007.

References 

  1. Doucette JW, Corl PD, Payne HM, Flynn AE, Goto M, Nassi M, et al. Validation of a Doppler guide wire for intravascular measurement of coronary artery flow velocity. Circulation. 1992;85:1899–1911
  2. Lemma M, Mangini A, Gelpi G, Innorta A, Danna P, Lavarra F, et al. Effects of heart rate on phasic y-graft blood flow and flow reserve in patients with complete arterial myocardial revascularization: an intravascular Doppler catheter study. Eur J Cardiothorac Surg. 2003;24(1):81–85
  3. Muneretto C, Negri A, Manfredi J, et al. Safety and usefulness of composite grafts for total arteroial myocardial revascularization: a prospective randomized study. J Thorac Cardiovasc Surg. 2003;125:826–835
  4. Muneretto C, Bislei G, Nagri A, et al. Left internal thoracic artery–radial artery composite grafts as the technique of choice for myocardial revascularization in elderly patients: a prospective randomized evaluation. J Thorac Cardiovasc Surg. 2004;127:179–184
  5. Cameron A, Davis KB, Green G, Schaff HV. Coronary bypass surgery with internal-thoracic-artery grafts—effects on survival over a 15-year period. N Engl J Med. 1996;334(4):216–219
  6. Robertson MB, Köhler U, Hoskins PR, Marshall I. Flow in elliptical vessels calculated for a physiological waveform. J Vasc Res. 2001;38:73–82
  7. Perktold K, Hofer M, Rappitsch G, Loew M, Kuban BD, Friedman MH. Validated computation of physiologic flow in a realistic coronary artery branch. J. Biomech. 1998;(3):217–228
  8. Sheada RE, Cobbold RS, Johnston KW, Aarnink R. Three-dimensional display of calculated velocity profiles for physiological flow waveforms. J. Vasc. Surg. 1993;17(4):656–660
  9. Porenta G, Schima H, Pentaris A, Tsangaris S, Moertl D, Probst P, et al. Assessment of coronary stenoses by Doppler wires: a validation study using in vitro modeling and computer simulations. Ultrasound Med Biol. 1999;25(5):793–801
  10. Jenni R, Kaufmann PA, Jiang Z, Attenhofer C, Linka A, Mandinov L. In vitro validation of volumetric blood flow measurement using Doppler flow wire. Ultrasound Med Biol. 2000;26(8):1301–1310
  11. Jenni R, Matthews F, Aschkenasy SV, Lachat M, van Der Loo B, Oechslin E, et al. A novel in vivo procedure for volumetric flow measurements. Ultrasound Med Biol. 2004;30(5):633–637
  12. Womersley JR. Method for the calculation of velocity, rate of flow and viscous drag in arteries when the pressure gradient is known. J Physiol. 1955;127(3):553–563
  13. Nichols WW, O’Rourke MF. McDonald's Blood Flow in Arteries: Theoretic, Experimental and Clinical Principles. 5th ed.. London: Edward Arnold; 2005;
  14. Savader SJ, Lund GB, Osterman FA. Volumetric evaluation of blood flow in normal renal arteries with a Doppler flow wire: a feasibility study. J Vasc Interv Radiol. 1997;8(2):209–214
  15. Ponzini R, Vergara C, Redaelli A, Veneziani A. Reliable CFD-based estimation of flow rate in haemodynamics measures. Ultrasound Med Biol. 2006;32(10):1545–1555
  16. Charles A, Taylor , Mary T. Draney experimental and computational methods in cardiovascular fluid mechanics. Annu Rev Fluid Mech. 2004;36:197–231
  17. Migliavacca F, Dubini G. Computational modeling of vascular anastomoses. Biomech Model Mechanobiol. 2005;3(4):235–250
  18. Boutsianis E, Dave H, Frauenfelder T, Poulikakos D, Wildermuth S, Turina M, et al. Computational simulations of intra-coronary flow based on real coronary geometry. Eur J Cardio-Thorac Surg. 2004;26(2):248–256
  19. Politis AK, Stavropoulos GP, Christolis MN, Panagopoulos FG, Vlachos NS, Markatos NC. Numerical modeling of simulated blood flow in idealized composite arterial coronary grafts: steady state simulations. J Biomech. 2007;40(5):1125–1136
  20. Morbiducci U, Lemma M, Ponzini R, Boi A, Bondavalli L, Antona C, et al. Does the Ventrica magnetic vascular positioner (MVP(R)) for coronary artery bypass grafting significantly alter local fluid dynamics? A numeric study. Int J Artif Organs. 2007;30(7):628–639
  21. Morbiducci U, Ponzini R, Grigioni M, Redaelli A. Helical flow as fluid dynamic signature for atherogenesis risk in aortocoronary bypass. A numeric study. J Biomech. 2007;40(3):519–534
  22. Bloch KJ, Maki DG. Hyperviscosity syndrome associated with immunoglobulin abnormalities. J Sem Hematol. 1973;10:113–126
  23. Quarteroni A, Ragni S, Veneziani A. Coupling between lumped and distributed models for blood flow problems. Comput Vis Sci. 2001;4:111–124
  24. Laganà K, Dubini G, Migliavacca F, Pietrabissa R, Pennati G, Veneziani A, et al. Multiscale modelling as a tool to prescribe realistic boundary conditions for the study of surgical procedures. Biorheology. 2002;39:359–364
  25. Mantero S, Pietrabissa R, Fumero R. The coronary bed and its role in the cardiovascular system: a review and an introductory single-branch model. J Biomed Eng. 1992;14:109–115
  26. Steinman DA, Ethier CR. The effect of wall distensibility in a two-dimensional end-to-side anastomosis. J Biomech Eng. 1994;116:294–301
  27. Zeng D, Ding Z, Friedman MH, Ethier CR. Effects of cardiac motion on right coronary artery hemodynamics. Ann Biomed Eng. 2003;31:420–429
  28. Joshi AK, Leask RL, Myers JG, Ojha M, Butany J, Ethier CR. Intimal thickness is not associated with wall shear stress patterns in the human right coronary artery. Arterioscler Thromb Vasc Biol. 2004;24:2408–2413

PII: S1350-4533(07)00159-2

doi: 10.1016/j.medengphy.2007.09.004

Medical Engineering & Physics
Volume 30, Issue 7 , Pages 809-816 , September 2008

Article Tools

* Image Usage & Resolution