Medical Engineering & Physics
Volume 30, Issue 6 , Pages 671-679 , July 2008

Rheometry and associated techniques for blood coagulation studies

  • P.A. Evans

      Affiliations

    • Division of Clinical Haemorheology, Swansea NHS Trust Hospital, Morriston, Swansea, UK
    • ,
  • K. Hawkins

      Affiliations

    • Centre for Complex Fluids Processing, School of Engineering, Swansea University, Singleton Park, Swansea SA2 8PP, UK
    • ,
  • M. Lawrence

      Affiliations

    • Centre for Complex Fluids Processing, School of Engineering, Swansea University, Singleton Park, Swansea SA2 8PP, UK
    • ,
  • R.L. Williams

      Affiliations

    • Centre for Complex Fluids Processing, School of Engineering, Swansea University, Singleton Park, Swansea SA2 8PP, UK
    • ,
  • M.S. Barrow

      Affiliations

    • Centre for Complex Fluids Processing, School of Engineering, Swansea University, Singleton Park, Swansea SA2 8PP, UK
    • ,
  • N. Thirumalai

      Affiliations

    • Division of Clinical Haemorheology, Swansea NHS Trust Hospital, Morriston, Swansea, UK
    • ,
  • P.R. Williams

      Affiliations

    • Centre for Complex Fluids Processing, School of Engineering, Swansea University, Singleton Park, Swansea SA2 8PP, UK
    • Corresponding Author InformationCorresponding author.

Received 1 March 2007 ,Revised 13 August 2007 ,Accepted 14 August 2007.

References 

  1. Bailey K, Bettelheim FR, Lorand L, Middlebrook WR. Action of thrombin in the clotting of fibrinogen. Nature. 1951;167:233–234
  2. Weisel JW. The mechanical properties of fibrin for basic scientists and clinicians. Biophys Chem. 2004;112:267–276
  3. Isogai Y, Iida A, Chikatsu L, Mochizuki K, Abe M. Dynamic viscoelasticity of blood during clotting in health and disease. Biorheology. 1973;10:411–424
  4. Chmiel H, Anadere I, Walitza E. The determination of blood viscoelasticity in clinical hemorheology. Biorheology. 1990;27:883–894
  5. Scrutton MC, Ross-Murphy SB, Bennett GM, Stirling Y, Meade TW. Changes in clot deformability—a possible explanation for the epidemiologic association between plasma-fibrinogen concentration and myocardial-infarction. Blood Coagul Fibrinol. 1994;5:719–723
  6. Thurston GB, Henderson NM. Theoretical and applied rheology. In: Proceedings of the XIth international congr. rheology. Elsevier; 1992;p. 741
  7. Scott-Blair GW. An introduction to biorheology. Amsterdam: Elsevier Scientific; 1974;
  8. Ryan EA, Mockros LF, Weisel JW, Lorand L. Structural origins of fibrin clot rheology. Biophys J. 1999;77:2813–2826
  9. Ferri F, Greco M, Arcovito G, De Spirito M, Rocco M. Structure of fibrin gels studied by elastic light scattering techniques: dependence of fractal dimension, gel crossover length, fibre diameter, and fibre density on monomer concentration. Phys Rev E. 2002;66:11913
  10. Blomback B, Bark N. Fibrinopeptides and fibrin gel structure. Biophys Chem. 2004;112:147–151
  11. Brown BA. Hematology: principles and procedures. 4th ed.. Philadelphia: Lea and Febiger; 1993;
  12. Sultan C, Gouault-Heilmann GM, Imbert M. Manual of hematology. New York: Wiley; 1984;
  13. Lermusiaux P, How TV, Black RA. A new device for in vitro evaluation of thrombogenecity. Med Eng Phys. 2006;28:389–393
  14. Mallett SV, Cox DJA. Thromboelastography. Br J Anaesth. 1992;69:307–313
  15. Thurston GB. In:  Howe TC editors. Advances in hemodynamics and hemorheology. JAI Press; 1996;p. 1–30
  16. Scott-Blair GW, Burnett J. Thromboelastography of Newtonian fluids. Biorheology. 1968;5:177
  17. Kaibara M, Fukada E. Dynamic viscoelastic study for the structure of fibrin networks in the clots of blood and plasma. Biorheology. 1970;6:329–339
  18. Roberts WW, Lorand LL, Mockros LF. Viscoelastic properties of fibrin clots. Biorheology. 1973;10:29–42
  19. Burghardt WR, Goldstick TK, Leneschmidt J, Kempka K. Nonlinear viscoelasticity and thromboelastograph. 1. Studies on bovine plasma clots. Biorheology. 1995;32:621–630
  20. Riha P, Wang X, Liao R, Stoltz JF. Elasticity and fracture strain of whole blood clots. Clin Hemorheol Microcirc. 1999;21:45–49
  21. Williams PR, Hawkins K, Wright C, Evans PA, Simpkin H, Barrow MS, et al. Rheometrical and computational studies of blood viscoelasticity during coagulation. Clin Hemorheol Microcirc. 2006;35:123–127
  22. Henderson NM, Thurston CB. A new method for the analysis of blood and plasma coagulation. Biomed Sci Instrum. 1993;29:95–102
  23. Fukada E, Kaibara M. Rheological measurements of fibrin gels during clotting. Thromb Res Suppl II. 1976;8:49–58
  24. Fukada E, Sugiura Y, Date M, Kaibara M. Methods to study rheological properties of blood during clotting. Biorheol Suppl I. 1984;9–14
  25. Evans PA, Hawkins K, Williams RL, Williams PR. Rheometrical detection of incipient blood clot formation by Fourier transform mechanical spectroscopy. J. Non-Newton Fluid Mech 2007; in press, doi:10.1016/j.jnnfm.2007.04.020.
  26. Chambon F, Winter HH. Linear viscoelasticity at the gel-point of a cross-linking PDMS with imbalanced stoichiometry. J Rheol. 1987;31:683–697
  27. Mours M, Winter HH. Time-resolved rheometry. Rheol Acta. 1994;33:385–397
  28. Holly EE, Venkataraman SK, Chambon F, Winter HH. Fourier transform mechanical spectroscopy of viscoelastic materials with transient structure. J Non-Newton Fluid Mech. 1988;27:17–26
  29. Jones R, Ravji S, Hawkins K, Williams PR, Williams RL. An assessment of dispersion-induced errors in shear wave propagation measurements in critical gel and pre-gel point fluids. J Non-Newton Fluid Mech. 2004;124:11–24
  30. Hawkins, K, Lawrence M, Williams, PR, Williams RL. A study of gelatin gelation by Fourier transform mechanical spectroscopy. J. Non-Newton Fluid Mech 2007; in press, doi:10.1016/j.jnnfm.2007.05.016.
  31. Glover CJ, McIntire LV, Brown CH, Natelson EA. Mechanical trauma effect on clot structure formation. Thromb Res. 1977;10:11–25
  32. Kaibara M, Kawamoto Y. Rheological measurement of blood coagulation in vascular vessel model tube consisting of endothelial cells monolayer. Biorheology. 1991;28:263–274
  33. Karino T, Goldsmith HL. Adhesion of human platelets to collagen on the walls distal to a tubular expansion. Microvas Res. 1979;17:238–262
  34. Karino T, Goldsmith HL. Role of cell-wall interactions in thrombogenesis and atherogenesis. A microrheological study. Biorheology. 1984;21:587–601
  35. Sakharov DV, Nagelkerke JF, Rijken D. Rearrangements of the fibrin network and spatial distribution of fibrinolytic components during plasma clot lysis. J Biol Chem. 1996;271:2133–2138
  36. Ranby M, Ramstrom S, Svensson PO, Lindahl TL. Clotting time by free oscillation rheometry and visual inspection and a viscoelastic description of the clotting phenomenon. Scand J Clin Lab Invest. 2003;63:397–406
  37. Kaibara M, Date M. A new rheological method for measuring the coagulation process of blood contacting foreign surface. In:  Fung YC,  Hayashi K,  Seguchi Y editor. Progress and new directions of biomechanics. Tokyo: Mita Press; 1989;p. 63–71
  38. Hansson KM, Tengvall P, Lundstrom I, Ranby M, Lindahl TL. Surface plasmon resonance and free oscillation rheometry in combination: a useful approach for studies on haemostasis and interactions between whole blood and artificial surfaces. Biosens Bioelectron. 2002;17:747–759
  39. Alvaredo CHF, Machado JC. Measurement of plasma clotting time using ultrasonic shear waves. Physiol Meas. 1994;15:309–316
  40. Shung KK, Fei D, Yuan Y, Reeves WC. Ultrasonic characterization of blood during coagulation. J Clin Ultrasound. 1984;12:147–153
  41. Davies AR, Morgan D, Williams PR. Relating the relaxation spectrum to wave dispersion measurements. J Non-Newton Fluid Mech. 2004;124:25–35
  42. Viola F, Kramer MD, Lawrence MB, Oberhauser JP, Walker WF. Sonorheometry: a noncontact method for the dynamic assessment of thrombosis. Ann Biomed Eng. 2004;32:696–705
  43. Bandey HL, Cernosek RW, Lee WE, Ondrovic LE. Blood rheological characterization using the thickness-shear mode resonator. Biosens Bioelectron. 2004;19:1657–1665
  44. Chapin JW, Becker GL, Hurlbert BJ, Newland MC, Cuka DJ, Wood RP, et al. Comparison of thromboelastograph and Sonoclot coagulation analyzer for assessing coagulation status during orthoptic liver transplantation. Transplant Proc. 1989;21:3539
  45. Furuhashi M, Ura N, Hasegawa K, Yoshida H, Tsuchihashi K, Miura T, et al. Sonoclot coagulation analysis: new bedside monitoring for determination of the appropriate heparin dose during haemodialysis. Nephrol Dial Transplant. 2002;17:1457–1462
  46. Samra SK, Harrison RL, Bee DE, Valero V. A study of aspirin induced changes in bleeding time, platelet aggregation, and Sonoclot coagulation analysis in humans. Ann Clin Lab Sci. 1991;21:315–327
  47. Vikinge TP, Hansson KM, Benesch J, Johansen K, Ranby M, Lindahl TL, et al. Blood plasma coagulation studied by surface plasmon resonance. J Biomed Optics. 2000;5:51–55
  48. Hansson KM, Vikinge TP, Ranby M, Tengvall P, Lundstrom I, Johansen K, et al. Surface plasmon resonance (SPR) analysis of coagulation in whole blood with application in prothrombin time assay. Biosens Bioelectron. 1999;14:671–682
  49. Barrow MS, Bowen WR, Hilal N, Al-Hussany A, Williams PR, Williams RL, et al. A study of the tensile properties of thin fluid films in an atomic force microscope. Proc. Roy. Soc. A: Math Phys Sci. 2003;459:2885–2908
  50. Blinc A, Magdic J, Fric J, Musevic I. Atomic force microscopy of fibrin networks and plasma clots during fibrinolysis. Fibrinolysis Proteolysis. 2000;14:288–299
  51. Vikinge TP, Hansson KM, Sandstrom P, Liedberg B, Lindahl TL, Lundstrom I, et al. Comparison of surface plasmon resonance and quartz crystal microbalance in the study of whole blood and plasma coagulation. Biosens Bioelectron. 2000;15:605–613
  52. Sauerbrey G. Verwendung von Schwingquarzen zur Wägung dünner Schichten und zur Mikrowägung. Z Phys. 1959;155:206–222
  53. Rodahl M, Hook F, Krozer A, Brzezinski P, Kasemo B. Quartz-crystal microbalance setup for frequency and q-factor measurements in gaseous and liquid environments. Rev Sci Instrum. 1995;66:3924–3930
  54. Andersson M, Sellborn A, Fant C, Gretzer C, Elwing H. Acoustics of blood plasma on solid surfaces. J Biomater Sci: Polym Ed. 2002;13:907–917
  55. Andersson M, Andersson J, Sellborn A, Berglin M, Nilsson B, Elwing H. Quartz crystal microbalance-with dissipation monitoring (QCM-D) for real time measurements of blood coagulation density and immune complement activation on artificial surfaces. Biosens Bioelectron. 2005;21:79–86
  56. Puckett LG, Lewis JK, Urbas A, Cui XD, Gao DY, Bachas LG. Magnetoelastic transducers for monitoring coagulation, clot inhibition, and fibrinolysis. Biosens Bioelectron. 2005;20:1737–1743
  57. Cheng TJ, Chang HC, Lin TM. A piezoelectric quartz crystal sensor for the determination of coagulation time in plasma and whole blood. Biosens Bioelectron. 1998;13:147–156

PII: S1350-4533(07)00154-3

doi: 10.1016/j.medengphy.2007.08.005

Medical Engineering & Physics
Volume 30, Issue 6 , Pages 671-679 , July 2008

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