Medical Engineering & Physics
Volume 30, Issue 3 , Pages 329-340 , April 2008

Blood flow dynamics in patient-specific cerebral aneurysm models: The relationship between wall shear stress and aneurysm area index

  • Alvaro Valencia

      Affiliations

    • Department of Mechanical Engineering, Universidad de Chile, Casilla 2777, Santiago, Chile
    • Corresponding Author InformationCorresponding author.
    • ,
  • Hernan Morales

      Affiliations

    • Department of Mechanical Engineering, Universidad de Chile, Casilla 2777, Santiago, Chile
    • ,
  • Rodrigo Rivera

      Affiliations

    • Instituto de Neurocirugía Asenjo, Jose Manuel Infante 553, Santiago, Chile
    • ,
  • Eduardo Bravo

      Affiliations

    • Instituto de Neurocirugía Asenjo, Jose Manuel Infante 553, Santiago, Chile
    • ,
  • Marcelo Galvez

      Affiliations

    • Instituto de Neurocirugía Asenjo, Jose Manuel Infante 553, Santiago, Chile

Received 27 October 2006 ,Revised 13 April 2007 ,Accepted 19 April 2007.

References 

  1. Schievink WI. Intracranial aneurysms. N Engl J Med. 1997;336:28–40
  2. Barrocas A, Derdeyn C, Cross D, Moran Ch, Dacey R. Histologic and hemodynamic effects of endosaccular platinum coils for intracranial aneurysms. J Long-Term Eff Med Implants. 2004;14:225–242
  3. MacDonald DJ, Finlay HM, Canham PB. Directional wall strength in saccular brain aneurysms from polarized light microscopy. Ann Biomed Eng. 2000;28:533–542
  4. Hsiai TK, Cho SK, Honda HM, Hama S, Navab M, Demer LL, et al. Endothelial cell dynamics under pulsating flows: significance of high versus low shear stress slew rates (∂τ/∂t). Ann Biomed Eng. 2002;30:646–656
  5. Weir B, Amidei C, Kongable G, Findlay JM, Kassell NF, Kelly J, et al. The aspect ratio (dome/neck) of ruptured and unruptured aneurysms. J Neurosurg. 2003;99:447–451
  6. Ujiie H, Tachibana H, Hiramatsu O, Hazel AL, Matsumoto T, Ogasawara Y, et al. Effects of size and shape (aspect ratio) on the hemodynamics of saccular aneurysms: a possible index for surgical treatment of intracranial aneurysms. Neurosurgery. 1999;45:119–130
  7. Tateshima S, Murayama Y, Villablanca JP, Morino T, Nomura K, Tanishita K, et al. In vitro measurements of fluid-induced wall shear stress in unruptured cerebral aneurysms harboring blebs. Stroke. 2003;34:187–192
  8. Hoi Y, Meng H, Woodward SH, Bendok BR, Hanel RA, Guterman LR, et al. Effects of arterial geometry on aneurysm growth: three-dimensional computational fluid dynamics study. J Neurosurg. 2004;101:676–681
  9. Shojima M, Oshima M, Takagi K, Torii R, Hayakawa M, Katada K, et al. Magnitude and role of wall shear stress on cerebral aneurysm computational fluid dynamic study of 20 middle cerebral artery aneurysms. Stroke. 2004;35:2500–2505
  10. Hassan T, Timofeev EV, Saito T, Shimizu H, Ezura M, Tominaga T, et al. Computational replicas: anatomic reconstructions of cerebral vessels as volume numerical grids at three-dimensional angiography. Am J Neuroradiol. 2004;25:1356–1365
  11. Tateshima S, Viñuela F, Villablanca JP, Murayama Y, Morino T, Nomura K, et al. Three-dimensional blood flow analysis in a wide necked internal carotid artery-ophthalmic artery aneurysm. J Neurosurg. 2003;99:526–533
  12. Jou LD, Wong G, Dispensa B, Lawton MT, Higashida RT, Young WT, et al. Correlation between Lumenal geometry changes and hemodynamics in fusiform intracranial aneurysms. AJNR Am J Neuroradiol. 2005;26:2357–2363
  13. Steinman DA, Milner JS, Norley CJ, Lownie SP, Holdsworth DW. Image-based computational simulation of flow dynamics in a giant intracranial aneurysm. Am J Neuroradiol. 2003;24:559–566
  14. Chatziprodromou I, Butty V, Makhijani VB, Poulikakos D, Ventikos Y. Pulsatile blood flow in anatomically accurate vessels with multiple aneurysms: a medical intervention planning application of computational haemodynamics. Flow Turbulence Combust. 2003;71:333–346
  15. Cebral JR, Castro MA, Burgess JE, Pergolizzi RS, Sheridan MJ, Putman ChM. Characterization of cerebral aneurysms for assessing risk of rupture by using patient-specific computational hemodynamics models. Am J Neuroradiol. 2005;26:2550–2559
  16. Cebral JR, Castro MA, Appanaboyina S, Putman ChM, Millan D, Frangi AF. Efficient pipeline for image-based patient-specific analysis of cerebral aneurysm hemodynamics: technique and sensitivity. IEEE Trans Med Imaging. 2005;24:457–467
  17. Valencia AA, Guzman AM, Finol EA, Amon CH. Blood flow dynamics in saccular aneurysm models of the basilar artery. J Biomech Eng. 2006;128:516–526
  18. Valencia A, Zarate A, Galvez M, Badilla L. Non-Newtonian blood flow dynamics in a right internal carotid artery with a saccular aneurysm. Int J Numer Methods Fluids. 2006;50:751–764
  19. Low M, Perktold K, Raunig R. Hemodynamics in rigid and distensible saccular aneurysms: a numerical study of pulsatile flow characteristics. Biorheology. 1993;30:287–298
  20. Valencia A, Solis F. Blood flow dynamics and arterial wall interaction in a saccular aneurysm model of the basilar artery. Comput Struct. 2006;84:1326–1337
  21. Torii R, Oshima M, Kobayashi T, Takagi K, Tezduyar T. Influence of wall elasticity in patient-specific hemodynamic simulations. Comput Fluids. 2007;36:160–168
  22. Ma B, Harbaugh RE, Raghavan ML. Three-dimensional geometrical characterization of cerebral aneurysms. Ann Biomed Eng. 2004;32:264–273
  23. Raghavan ML, Ma B, Harbaugh RE. Quantified aneurysm shape and rupture risk. J Neurosurg. 2005;102:355–362
  24. Kim S. A study of non-Newtonian viscosity and yield stress of blood in a scanning capillary-tube rheometer. Thesis. Philadelphia, PA: Drexel University; 2002.
  25. Johnston BM, Johnston PR, Corney S, Kilpatrick D. Non-Newtonian blood flow in human right coronary arteries: steady state simulations. J Biomech. 2004;37:709–720
  26. Zamir M. The physics of pulsatile flow. New York: Springer-Verlag; 2000;
  27. Ferziger JH, Peric M. Computational methods for fluid dynamics. Berlin: Springer-Verlag; 1997;
  28. Meng H, Swartz D, Wang Z, Hoi Y, Kolega J, Metaxa E, et al. Vivo hemodynamics correlated with vascular responses associated with cerebral aneurysm development. In: 5th World Congress of Biomechanics, Dieter Liepsch Editor, Munich Germany, July 29–August 4. 2006;p. 479–483MEDIMOND
  29. Chatziprodromou I, Tricoli A, Poulikakos D, Ventikos Y. Haemodynamics and wall remodeling of a growing cerebral aneurysm: a computational model. J Biomech. 2007;40:412–426
  30. Pentimalli L, Modesti A, Vignati A, Marchese E, Albanese A, Di Rocco F, et al. Role of apoptosis in intracranial aneurysm rupture. J Neurosurg. 2004;101:1018–1025

PII: S1350-4533(07)00080-X

doi: 10.1016/j.medengphy.2007.04.011

Medical Engineering & Physics
Volume 30, Issue 3 , Pages 329-340 , April 2008

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