Medical Engineering & Physics
Volume 29, Issue 10 , Pages 1073-1083 , December 2007

Extraction of spectral based measures from MEG background oscillations in Alzheimer's disease

  • Jesús Poza

      Affiliations

    • Grupo de Ingeniería Biomédica, E.T.S. Ingenieros de Telecomunicación, University of Valladolid, Camino del Cementerio s/n, 47011 Valladolid, Spain
    • Corresponding Author InformationCorresponding author. Tel.: +34 983 42300x5569; fax: +34 983 423667.
    • ,
  • Roberto Hornero

      Affiliations

    • Grupo de Ingeniería Biomédica, E.T.S. Ingenieros de Telecomunicación, University of Valladolid, Camino del Cementerio s/n, 47011 Valladolid, Spain
    • ,
  • Daniel Abásolo

      Affiliations

    • Grupo de Ingeniería Biomédica, E.T.S. Ingenieros de Telecomunicación, University of Valladolid, Camino del Cementerio s/n, 47011 Valladolid, Spain
    • ,
  • Alberto Fernández

      Affiliations

    • Centro de Magnetoencefalografía Dr. Pérez-Modrego, Facultad de Medicina, University Complutense of Madrid, Spain
    • ,
  • María García

      Affiliations

    • Grupo de Ingeniería Biomédica, E.T.S. Ingenieros de Telecomunicación, University of Valladolid, Camino del Cementerio s/n, 47011 Valladolid, Spain

Received 22 June 2006 ,Revised 14 November 2006 ,Accepted 22 November 2006.

References 

  1. Bird TD. Alzheimer's disease and other primary dementias. In:  Braunwald E,  Fauci AS,  Kasper DL,  Hauser SL,  Longo DL,  Jameson JL editor. Harrison's principles of internal medicine. New York: The McGraw-Hill Co. Inc.; 2001;p. 2391–2399
  2. Katzman R. Current research on Alzheimer's disease in a historical perspective. In:  Khachaturian ZS,  Radebaugh TS editor. Cause(s), diagnosis, treatment and care. Boca Raton, FL: CRC Press; 1996;p. 15–29
  3. Larson EB, Edwards JK, O’Meara E, Nochlin D, Sumi SM. Neuropathologic diagnostic outcomes from a cohort of outpatients with suspected dementia. J Gerontol. 1996;51:M313–M318
  4. Rasmusson DX, Brandt J, Steele C, Hedreen JC, Troncoso JC, Folstein MF. Accuracy of clinical diagnosis of Alzheimer disease and clinical features of patients with non-Alzheimer neuropathology. Alzheimer Dis Assoc Disord. 1996;10:180–188
  5. Rossor M. Alzheimer's disease. In:  Donaghy M editors. Brain's diseases of the nervous system. Oxford: Oxford University Press; 2001;p. 750–754
  6. Hämäläinen M, Hari R, Ilmoniemi RJ, Knuutila J, Lounasmaa OV. Magnetoencephalography—theory, instrumentation, and applications to non-invasive studies of the working human brain. Rev Mod Phys. 1993;65:413–497
  7. Hari R. Magnetoencephalography in clinical neurophysiological assessment of human cortical functions. In:  Niedermeyer E,  Lopes da Silva F editor. Electroencephalography: basic principles, clinical applications, and related fields. Philadelphia: Lippincott Williams & Wilkins; 2005;p. 1165–1197
  8. Jeong J. EEG dynamics in patients with Alzheimer's disease. Clin Neurophysiol. 2004;115:1490–1505
  9. Stam CJ. Nonlinear dynamical analysis of EEG and MEG: review of an emerging field. Clin Neurophysiol. 2005;116:2266–2301
  10. Coben LA, Danzinger WL, Storandt M. A longitudinal EEG study of mild senile dementia of Alzheimer type: changes at 1 year and at 2.5 years. Electroencephalogr Clin Neurophysiol. 1985;61:101–112
  11. Soininen H, Partanen J, Laulumaa V, Helkala E-L, Laakso M, Riekkinen PJ. Longitudinal EEG spectral analysis in early stage of Alzheimer's disease. Electroencephalogr Clin Neurophysiol. 1989;72:290–297
  12. Schreiter-Gasser U, Gasser T, Ziegler P. Quantitative EEG analysis in early onset Alzheimer's disease: a controlled study. Electroencephalogr Clin Neurophysiol. 1993;86:15–22
  13. Jelic V, Johansson S-E, Almkvist O, Shigeta M, Julin P, Nordberg A, et al. Quantitative electroencephalography in mild cognitive impairment: longitudinal changes and possible prediction of Alzheimer's disease. Neurobiol Aging. 2000;21:533–540
  14. Berendse HW, Verbunt JPA, Scheltens Ph , van Dijk BW, Jonkman EJ. Magnetoencephalographic analysis of cortical activity in Alzheimer's disease: a pilot study. Clin Neurophysiol. 2000;111:604–612
  15. Osipova D, Ahveninen J, Jensen O, Ylikoski A, Pekkonen E. Altered generation of spontaneous oscillations in Alzheimer's disease. NeuroImage. 2005;27:835–841
  16. Besthorn C, Förstl H, Geiger-Kabisch C, Sattel H, Gasser T, Schreiter-Gasser U. EEG coherence in Alzheimer disease. Electroencephalogr Clin Neurophysiol. 1994;90:242–245
  17. Adler G, Brassen S, Jajcevic A. EEG coherence in Alzheimer's dementia. J Neural Transm. 2003;110:1051–1058
  18. Franciotti R, Iacono D, Della Penna S, Pizzella V, Torquati K, Onofrj M, et al. Cortical rhythms reactivity in AD, LBD and normal subjects. A quantitative MEG study. Neurobiol Aging. 2006;27:1100–1109
  19. Jeong J, Kim SJ, Han SH. Non-linear dynamical analysis of the EEG in Alzheimer's disease with optimal embedding dimension. Electroencephalogr Clin Neurophysiol. 1998;106:220–228
  20. Jeong J, Chae JH, Kim SY, Han SH. Nonlinear dynamic analysis of the EEG in patients with Alzheimer's disease and vascular dementia. J Clin Neurophysiol. 2001;18:58–67
  21. Stam CJ, van der Made Y, Pijnenburg YA, Scheltens P. EEG synchronization in mild cognitive impairment and Alzheimer's disease. Acta Neurol Scand. 2003;108:90–96
  22. Abásolo D, Hornero R, Espino P, Poza J, Sánchez CI, de la Rosa R. Analysis of regularity in the EEG background activity of Alzheimer's disease patients with approximate entropy. Clin Neurophysiol. 2005;116:1826–1834
  23. Abásolo D, Hornero R, Gómez C, García M, López M. Analysis of EEG background activity in Alzheimer's disease patients with Lempel–Ziv complexity and central tendency measure. Med Eng Phys. 2006;28:315–322
  24. Abásolo D, Hornero R, Espino P, Álvarez D, Poza J. Entropy analysis of the EEG background activity in Alzheimer's disease patients. Physiol Meas. 2006;27:241–253
  25. Gómez C, Hornero R, Abásolo D, Fernández A, López M. Complexity analysis of the magnetoencephalogram background activity in Alzheimer's disease patients. Med Eng Phys. 2006;28:851–859
  26. van Cappellen van Walsum A-M, Pijnenburg YAL, Berendse HW, van Dijk BW, Knol DL, Scheltens Ph, et al. A neural complexity measure applied to MEG data in Alzheimer's disease. Clin Neurophysiol. 2003;114:1034–1040
  27. Jelles B, van Birgelen JH, Slaets JPJ, Hekster REM, Jonkman EJ, Stam CJ. Decrease of non-linear structure in the EEG of Alzheimer patients compared to healthy controls. Clin Neurophysiol. 1999;110:1159–1167
  28. Signorino M, Pucci E, Belardinelli N, Nolfe G, Angeleri F. EEG spectral analysis in vascular and Alzheimer dementia. Electroencephalogr Clin Neurophysiol. 1995;94:313–325
  29. Rodríguez G, Copello F, Vitali P, Perego G, Nobili F. EEG spectral profile to stage Alzheimer's disease. Clin Neurophysiol. 1999;110:1831–1837
  30. Signorino M, Pucci E, Brizioli E, Cacchio G, Nolfe G, Angeleri F. EEG power spectrum typical of vascular dementia in a subgroup of Alzheimer patients. Arch Gerontol Geriatr. 1996;23:139–151
  31. Pucci E, Cacchiò G, Angeloni R, Belardinelli N, Nolfe G, Signorino M, et al. EEG spectral analysis in Alzheimer's disease and different degenerative dementias. Arch Gerontol Geriatr. 1998;26:283–297
  32. Ihl R, Dierks T, Martin E-M, Frölich L, Maurer K. Topography of the maximum of the amplitude of EEG frequency bands in dementia of the Alzheimer type. Biol Psychiatry. 1996;39:319–325
  33. Penttilä M, Partanen JV, Soininen H, Riekkinen PJ. Quantitative analysis of occipital EEG in different stages of Alzheimer's disease. Electroencephalogr Clin Neurophysiol. 1985;60:1–6
  34. Brenner RP, Ulrich RF, Spiker DG, Sclabassi RJ, Reynolds CF, Marin RS, et al. Computerized EEG spectral analysis in elderly normal, demented and depressed subjects. Electroencephalogr Clin Neurophysiol. 1986;64:483–492
  35. Moretti DV, Babiloni C, Binetti G, Cassetta E, Dal Forno G, Ferreri F, et al. Individual analysis of EEG frequency and band power in mild Alzheimer's disease. Clin Neurophysiol. 2004;115:299–308
  36. Fernández A, Hornero R, Mayo A, Poza J, Gil-Gregorio P, Ortiz T. MEG spectral profile in Alzheimer's disease and mild cognitive impairment. Clin Neurophysiol. 2006;117:306–314
  37. Fernández A, Maestú F, Amo C, Gil P, Fehr T, Wienbruch C, et al. Focal temporoparietal slow activity in Alzheimer's disease revealed by magnetoencephalography. Biol Psychiatry. 2002;52:764–770
  38. Grouven U, Beger FA, Schultz B, Schultz A. Correlation of Narcotrend index, entropy measures, and spectral parameters with calculated propofol effect-site concentrations during induction of propofol-remifentanil anaesthesia. J Clin Monit Comput. 2004;18:231–240
  39. Tonner PH, Bein B. Classic electroencephalographic parameters: median frequency, spectral edge frequency etc. Best Pract Res Clin Anaesthesiol. 2006;20:147–159
  40. Schwender D, Daunderer M, Mulzer S, Klasing S, Finsterer U, Peter K. Spectral edge frequency of the electroencephalogram to monitor depth of anaesthesia with isoflurane or propofol. Br J Anaesth. 1996;77:179–184
  41. Folstein MF, Folstein SE, McHugh PR. Mini-mental state. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12:189–198
  42. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of NINCDS-ADRDA work group under the auspices of department of health and human services task force on Alzheimer's disease. Neurology. 1984;34:939–944
  43. Klimesch W. EEG alpha and theta oscillations reflect cognitive and memory performance: a review analysis. Brain Res Rev. 1999;29:169–195
  44. Hudson RJ, Stanski DR, Saidman LJ, Meathe E. A model for studying depth of anesthesia and acute tolerance to thiopental. Anesthesiology. 1986;65:19–27
  45. Inouye T, Shinosaki K, Sakamoto H, Toi S, Ukai S, Iyama A, et al. Quantification of EEG irregularity by use of the entropy of the power spectrum. Electroencephalogr Clin Neurophysiol. 1991;79:204–210
  46. Sleigh JW, Steyn-Ross DA, Grant C, Ludbrook G. Cortical entropy changes with general anaesthesia: theory and experiment. Physiol Meas. 2004;25:921–934
  47. Pollock V, Schneider L, Lyness S. EEG amplitudes in healthy, late–middle-aged and elderly adults: normality of the distributions and correlations with age. Electroencephalogr Clin Neurophysiol. 1990;75:276–288
  48. Jackson JE. A user's guide to principal components. New York: John Wiley & Sons; 1991;p. 41–51
  49. Ferré L. Selection of components in principal component analysis: a comparison of methods. Computat Stat Data Anal. 1995;19:669–682
  50. Jolliffe IT. Principal component analysis. New York: Springer; 2002;p. 112–33
  51. Hoaglin D, Mosteller F, Tukey J. Understanding robust and exploratory data analysis. New York: Wiley & Sons; 2000;
  52. Zweig MH, Campbell G. Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine. Clin Chem. 1993;39:561–577
  53. Osipova D, Ahveninen J, Kaakkola S, Jääskeläinen IP, Huttunen J, Pekkonen E. Effects of scopolamine on MEG spectral power and coherence in elderly subjects. Clin Neurophysiol. 2003;114:1902–1907
  54. Babiloni C, Cassetta E, Chiovenda P, Del Percio C, Ercolani M, Moretti DV, et al. Alpha rhythms in mild dements during visual delayed choice reaction time tasks: a MEG study. Brain Res Bull. 2005;65:457–470
  55. Prinz PN, Vitiell MV. Dominant occipital (alpha) rhythm frequency in early stage Alzheimer's disease and depression. Electroencephalogr Clin Neurophysiol. 1989;73:427–432
  56. Fernández A, Rodríguez-Palancas A, López-Ibor M, Zuluaga P, Turrero A, Maestú F, et al. Increased occipital delta dipole density in major depressive disorder determined by magnetoencephalography. J Psychiatry Neurosci. 2005;30:17–23
  57. Pin JC, Neau JP, Paquereau J, Rostykus C, Guehl D, Aubert I, et al. Comparative study by computerized EEG of dementia of the Alzheimer type and Parkinson's disease with dementia. Neurophysiol Clin. 1992;22:301–312
  58. Kotini A, Anninos P, Adamopoulos A, Prassopoulos P. Low-frequency MEG activity and MRI evaluation in Parkinson's disease. Brain Topogr. 2005;18:59–63
  59. Stigsby B, Jóhannesson G, Ingvar DH, Regional . EEG analysis and regional cerebral blood flow in Alzheimer's and Pick's diseases. Electroencephalogr Clin Neurophysiol. 1981;51:537–547
  60. Streletz LJ, Reyes PF, Zalewska M, Katz L, Fariello RG. Computer analysis of EEG activity in dementia of the Alzheimer's type and Huntington's disease. Neurobiol Aging. 1990;11:15–20

PII: S1350-4533(06)00246-3

doi: 10.1016/j.medengphy.2006.11.006

Medical Engineering & Physics
Volume 29, Issue 10 , Pages 1073-1083 , December 2007

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