Medical Engineering & Physics
Volume 29, Issue 10 , Pages 1084-1088, December 2007

Human hydration level monitoring using embedded piezoresistive microcantilever sensors

  • R. Stewart

      Affiliations

    • Cantimer, Inc., Menlo Park, CA 94025, United States
  • ,
  • J. Reed

      Affiliations

    • Cantimer, Inc., Menlo Park, CA 94025, United States
  • ,
  • J. Zhong

      Affiliations

    • Cantimer, Inc., Menlo Park, CA 94025, United States
  • ,
  • K. Morton

      Affiliations

    • Cantimer, Inc., Menlo Park, CA 94025, United States
  • ,
  • T.L. Porter

      Affiliations

    • Department of Physics, Northern Arizona University, Flagstaff, AZ 86011, United States
    • Corresponding Author InformationCorresponding author. Tel.: +1 928 523 2540.

Received 14 June 2006; received in revised form 13 November 2006; accepted 15 November 2006. published online 12 January 2007.

Abstract 

Embedded piezoresistive microcantilever (EPM) sensors were used to measure osmolality changes in both saliva mimic solutions and true human saliva. Osmolality changes in human saliva or urine may prove to be reliable, simple, and easy to measure markers for tracking human hydration levels. EPM sensors used in these experiments show good response to osmolality changes in both NaCl-based saliva mimic solutions and to human saliva. The addition of zero-point offset correction to EPM sensors allows for tracking of saliva osmolality changes with high accuracy. Also, the same EPM sensors exhibit a large enough range of osmolality response to make them potentially suitable for urine or blood serum osmolality monitoring.

Keywords: Hydration, Microcantilever, Saliva, Osmolality

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PII: S1350-4533(06)00235-9

doi:10.1016/j.medengphy.2006.11.003

Medical Engineering & Physics
Volume 29, Issue 10 , Pages 1084-1088, December 2007