Medical Engineering & Physics
Volume 29, Issue 10 , Pages 1096-1105 , December 2007

Accuracy of high-resolution peripheral quantitative computed tomography for measurement of bone quality

Received 29 August 2006 ,Revised 9 November 2006 ,Accepted 10 November 2006.

References 

  1. Kleerekoper M, Villanueva AR, Stanciu J, Rao DS, Parfitt AM. The role of three-dimensional trabecular microstructure in the pathogenesis of vertebral compression fractures. Calcif Tissue Int. 1985;37(6):594–597
  2. Peacock M, Turner CH, Econs MJ, Foroud T. Genetics of osteoporosis. Endocr Rev. 2002;23(3):303–326
  3. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. Geneva: World Health Organization; 1994;
  4. Müller R. The Zurich experience: one decade of three-dimensional high-resolution computed tomography. Top Magn Reson Imaging. 2002;13(5):307–322
  5. Osteoporosis prevention, diagnosis, and therapy. JAMA. 2001;285(6):785–795
  6. Cummings SR, Nevitt MC, Browner WS, Stone K, Fox KM, Ensrud KE, et al. Risk factors for hip fracture in white women. Study of Osteoporotic Fractures Research Group. N Engl J Med. 1995;332(12):767–773
  7. Hodsman AB, Kisiel M, Adachi JD, Fraher LJ, Watson PH. Histomorphometric evidence for increased bone turnover without change in cortical thickness or porosity after 2 years of cyclical hPTH(1-34) therapy in women with severe osteoporosis. Bone. 2000;27(2):311–318
  8. Zanchetta JR, Bogado CE, Ferretti JL, Wang O, Wilson MG, Sato M, et al. Effects of teriparatide [recombinant human parathyroid hormone (1–34)] on cortical bone in postmenopausal women with osteoporosis. J Bone Miner Res. 2003;18(3):539–543
  9. Rüegsegger P, Koller B, Müller R. A microtomographic system for the nondestructive evaluation of bone architecture. Calcif Tissue Int. 1996;58(1):24–29
  10. Feldkamp LA, Goldstein SA, Parfitt AM, Jesion G, Kleerekoper M. The direct examination of three-dimensional bone architecture in vitro by computed tomography. J Bone Miner Res. 1989;4(1):3–11
  11. Hildebrand T, Rüegsegger P. A new method for the model-independent assessment of thickness in three-dimensional images. J. Microsc. 1997;185(1):67–75
  12. Hildebrand T, Rüegsegger P. Quantification of bone microarchitecture with the structure model index. Comput Meth Biomech Biomed Eng. 1997;1:15–23
  13. Harrigan TP, Mann RW. Characterization of microstructural anisotropy in orthotropic materials using a second rank tensor. J Mater Sci. 1984;19:761–767
  14. Odgaard A, Gundersen HJ. Quantification of connectivity in cancellous bone, with special emphasis on 3-D reconstructions. Bone. 1993;14(2):173–182
  15. Müller R, Hahn M, Vogel M, Delling G, Rüegsegger P. Morphometric analysis of noninvasively assessed bone biopsies: comparison of high-resolution computed tomography and histologic sections. Bone. 1996;18(3):215–220[published erratum appears in Bone 1996;19(3):299]
  16. Laib A, Hauselmann HJ, Ruegsegger P. In vivo high resolution 3D-QCT of the human forearm. Technol Health Care. 1998;6(5–6):329–337
  17. Laib A, Ruegsegger P. Comparison of structure extraction methods for in vivo trabecular bone measurements. Comput Med Imaging Graph. 1999;23(2):69–74
  18. Kothari M, Keaveny TM, Lin JC, Newitt DC, Genant HK, Majumdar S. Impact of spatial resolution on the prediction of trabecular architecture parameters. Bone. 1998;22(5):437–443
  19. Parfitt AM, Mathews CH, Villanueva AR, Kleerekoper M, Frame B, Rao DS. Relationships between surface, volume, and thickness of iliac trabecular bone in aging and in osteoporosis. Implications for the microanatomic and cellular mechanisms of bone loss. J Clin Invest. 1983;72(4):1396–1409
  20. Boutroy S, Bouxsein ML, Munoz F, Delmas PD. In vivo assessment of trabecular bone microarchitecture by high-resolution peripheral quantitative computed tomography. J Clin Endocrinol Metab. 2005;90(12):6508–6515
  21. Khosla S, Riggs BL, Atkinson EJ, Oberg AL, McDaniel LJ, Holets M, et al. Effects of sex and age on bone microstructure at the ultradistal radius: a population-based noninvasive in vivo assessment. J Bone Miner Res. 2006;21(1):124–131
  22. Van Rietbergen B, Weinans H, Huiskes R, Odgaard A. A new method to determine trabecular bone elastic properties and loading using micromechanical finite-element models. J Biomech. 1995;28(1):69–81
  23. Hollister SJ, Fyhrie DP, Jepsen KJ, Goldstein SA. Application of homogenization theory to the study of trabecular bone mechanics. J Biomech. 1991;24(9):825–839
  24. Hollister SJ, Brennan JM, Kikuchi N. A homogenization sampling procedure for calculating trabecular bone effective stiffness and tissue level stress. J Biomech. 1994;27(4):433–444
  25. Van Rietbergen B, Odgaard A, Kabel J, Huiskes R. Direct mechanics assessment of elastic symmetries and properties of trabecular bone architecture. J Biomech. 1996;29(12):1653–1657
  26. Van Rietbergen B, Müller R, Ulrich D, Rüegsegger P, Huiskes R. Quantitative assessment of tissue loading in a proximal femur using a full scale microstructural FE-model. Trans Orthop Res Soc. 1997;22(p):p62
  27. Pistoia W, van Rietbergen B, Lochmuller EM, Lill CA, Eckstein F, Ruegsegger P. Estimation of distal radius failure load with micro-finite element analysis models based on three-dimensional peripheral quantitative computed tomography images. Bone. 2002;30(6):842–848
  28. Ulrich D, van Rietbergen B, Laib A, Ruegsegger P. Load transfer analysis of the distal radius from in-vivo high-resolution CT-imaging. J Biomech. 1999;32(8):821–828
  29. MacNeil JA, Boyd SK. Load distribution and the relation to morphological indices in the distal radius by high resolution peripheral quantitative computed tomography. American society for bone and mineral research 28th annual meeting, Philadelphia, PA, 2006;21(1):S87.
  30. Thomsen JS, Laib A, Koller B, Prohaska S, Mosekilde L, Gowin W. Stereological measures of trabecular bone structure: comparison of 3D micro computed tomography with 2D histological sections in human proximal tibial bone biopsies. J Microsc. 2005;218(Pt 2):171–179
  31. Müller R, Van Campenhout H, Van Damme B, Van Der Perre G, Dequeker J, Hildebrand T, et al. Morphometric analysis of human bone biopsies: a quantitative structural comparison of histological sections and micro-computed tomography. Bone. 1998;23(1):59–66
  32. Müller R, Hildebrand T, Rüegsegger P. Non-invasive bone biopsy: a new method to analyse and display the three-dimensional structure of trabecular bone. Phys Med Biol. 1994;39(1):145–164
  33. Lorensen WE, Cline HE. Marching cubes: a high resolution 3D surface construction algorithm. Comput Graphics. 1987;21(4):163–169
  34. Mattes D, Haynor DR, Vesselle H, Lewellen TK, Eubank W. PET-CT image registration in the chest using free-form deformations. IEEE Trans Med Imaging. 2003;22(1):120–128
  35. Mattes D, Haynor DR, Vesselle H, Lewellen TK, Eubank W. Non-rigid multi-modality image registration. In: Medical imaging 2001: image processing. 2001;p. 1609–1620
  36. Boyd SK, Moser S, Kuhn M, Klinck RJ, Krauze PL, Muller R, et al. Evaluation of three-dimensional image registration methodologies for in vivo micro-computed tomography. Ann Biomed Eng. 2006;34(10):1587–1599
  37. Boyd SK, Müller R, Zernicke RF. Mechanical and architectural bone adaptation in early stage experimental osteoarthritis. J Bone Miner Res. 2002;17(4):687–694
  38. Boyd SK, Müller R. Smooth surface meshing for automated finite element model generation from 3D image data. J Biomech. 2006;39:1287–1295
  39. Su R, Campbell GM, Boyd SK. Establishment of an architecture-specific experimental validation approach for finite element modeling of bone by rapid prototyping and high resolution computed tomography. Med Eng Phys 2006.
  40. Langton CM, Njeh CF. The physical measurement of bone Series in medical physics and biomedical engineering. Bristol, Philadelphia: Institute of Physics; 2004;p. xxvi, 612
  41. Formica CA, Nieves JW, Cosman F, Garrett P, Lindsay R. Comparative assessment of bone mineral measurements using dual X-ray absorptiometry and peripheral quantitative computed tomography. Osteoporos Int. 1998;8(5):460–467
  42. Boskey AL, Goldberg M, Kulkarni A, Gomez S. Infrared imaging microscopy of bone: Illustrations from a mouse model of Fabry disease. Biochim Biophys Acta. 2006;
  43. Boyd SK, Moser S, Kuhn M, Klinck RJ, Krauze P, Müller R, et al. Evaluation of three-dimensional image registration methodologies for in vivo micro-computed tomography. Ann Biomed Eng, 2006, submitted for publication.
  44. Body JJ, Gaich GA, Scheele WH, Kulkarni PM, Miller PD, Peretz A, et al. A randomized double-blind trial to compare the efficacy of teriparatide [recombinant human parathyroid hormone (1-34)] with alendronate in postmenopausal women with osteoporosis. J Clin Endocrinol Metab. 2002;87(10):4528–4535
  45. Neer RM, Arnaud CD, Zanchetta JR, Prince R, Gaich GA, Reginster JY, et al. Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis. N Engl J Med. 2001;344(19):1434–1441
  46. Lane NE, Thompson JM, Haupt D, Kimmel DB, Modin G, Kinney JH. Acute changes in trabecular bone connectivity and osteoclast activity in the ovariectomized rat in vivo. J Bone Miner Res. 1998;13(2):229–236
  47. Kinney JH, Ladd AJ. The relationship between three-dimensional connectivity and the elastic properties of trabecular bone. J Bone Miner Res. 1998;13(5):839–845
  48. Yeni YN, Christopherson GT, Dong XN, Kim DG, Fyhrie DP. Effect of microcomputed tomography voxel size on the finite element model accuracy for human cancellous bone. J Biomech Eng. 2005;127(1):1–8
  49. Pistoia W, van Rietbergen B, Laib A, Ruegsegger P. High-resolution three-dimensional-pQCT images can be an adequate basis for in-vivo microFE analysis of bone. J Biomech Eng. 2001;123(2):176–183

PII: S1350-4533(06)00233-5

doi: 10.1016/j.medengphy.2006.11.002

Medical Engineering & Physics
Volume 29, Issue 10 , Pages 1096-1105 , December 2007

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