Medical Engineering & Physics
Volume 29, Issue 8 , Pages 829-839 , October 2007

Modeling, analysis, and validation of a pneumatically driven left ventricle for use in mock circulatory systems

Received 12 June 2006 ,Revised 25 August 2006 ,Accepted 10 September 2006.

References 

  1. Donovan FMJ. Design of a hydraulic analog of the circulatory system of evaluating artificial hearts. Biomater Med Dev Artif Organs. 1975;3(4):439–449
  2. Rosenberg G, Phillips WM, Landis DL, Pierce WS. Design and evaluation of the Pennsylvania State University mock circulation system. ASAIO J. 1981;4(1):41–49
  3. Knierbein B, Reul H, Eilers R, Lange M, Kaufmann R, Rau G. Compact mock loops of the systemic and pulmonary circulation for blood pump testing. Int J Artif Organs. 1992;15(1):40–48
  4. Vandenberghe S, Segers P, Meyns B, Verdonck P. Hydrodynamic characterization of ventricular assist devices. Int J Artif Organs. 2001;24(7):470–477
  5. Pantalos GM, Koenig SC, Gillars KJ, Giridharan GA , Ewert DL. Characterization of an adult mock circulation for testing cardiac support devices. ASAIO J. 2004;50(1):37–46
  6. Liu Y, Allaire P, Wood H, Olsen D. Design and initial testing of a mock human circulatory loop for left ventricular assist device performance testing. Artif Organs. 2005;29(4):341–345
  7. Koenig SC, Pantalos GM, Gillars KJ, Ewert DL, Litwak KN, Etoch SW. Hemodynamic and pressure–volume responses to continuous and pulsatile ventricular assist in adult mock circulation. ASAIO J. 2004;50(1):15–24
  8. Vandenberghe S, Segers P, Josemans H, Van Loon JP, Rakhorst G, Verdonck P. In vitro assessment of the unloading and perfusion capacities of the PUCA II and the IABP. Perfusion. 2004;19:25–32
  9. Jin W, Clark C. Experimental investigation of unsteady flow behaviour within a sac-type ventricular assist device (VAD). J Biomech. 1993;26(6):697–707
  10. Jin W, Clark C. Pressure development within a sac-type pneumatically driven ventricular assist device. J Biomech. 1994;27(11):1319–1329
  11. Baloa LA, Boston JR, Antaki JF. Elastance-based control of a mock circulatory system. Ann Biomed Eng. 2001;29:244–251
  12. Ferrari G, Kozarski M, De Lazzari C, Gorczynska K, Tosti G, Darowski M. Development of a hybrid (numerical-hydraulic) circulatory model: prototype testing and its response to IABP assistance. Int J Artif Organs. 2005;28(7):750–759
  13. Colacino FM, Arabia M, Danieli GA, Moscato F, Nicosia S, Piedimonte F, et al. Hybrid test bench for evaluation of any device related to mechanical cardiac assistance. Int J Artif Organs. 2005;28(8):817–826
  14. Sagawa K, Maughan L, Suga H, Sunagawa K. Cardiac contraction and the pressure–volume relationship. New York: Oxford University Press; 1988;
  15. Guyton Arthur C, Jones Carl E, Coleman Thomas G. Circulatory physiology: cardiac output and its regulation. 2nd ed.. Philadelphia: W.B. Saunders; 1973;
  16. Pantalos GM, Hayes J, Khanwilkar P, Bearnson G, Olsen D. Left ventricular simulator for cardiovascular device testing. ASAIO J. 1996;42:46
  17. Guerrisi M, Arabia M, Gerardi T, Tosti G. Technical and functional solutions for the total artificial heart, in Elettromedicali. 1985; 16–42.
  18. Arabia M, Gerardi T. Prostheses and biomaterials, in Elettromedicali. 1985; 70–86.
  19. Rideout VC, Dick DE. Difference–differential equations for fluid flow in distensible tubes. IEEE Trans Biomed Eng. 1967;BME-14(3):171–177
  20. Frank O. Die grundform des arterielen pulses erste abhandung: mathematische analyse. Z Biol. 1899;37:483–526
  21. Guyton Arthur C, Coleman Thomas G, Grancger HJ. Circulation: overall regulation. Annu Rev Physiol. 1972;34:13–46
  22. Phillips WM. Design criteria and evaluation of a sac artificial heart. Adv Cardiovasc Phys. 1983;5(4):184–215
  23. Arabia M, Akutsu T. A new test circulatory system for research in cardiovascular engineering. Ann Biomed Eng. 1984;12:29–48
  24. Campbell KB, Ringo JA, Neti C, Alexander JE. Informational analysis of interaction between the left ventricle and the systemic arteries. Ann Biomed Eng. 1984;12:209–231
  25. Guyton Arthur C, Hall John E. Fisiologia medica. Xth ed.. Napoli: W.B. Saunders Company; 2000;
  26. Stergiopulos N, Westerhof BE, Westerhof N. Total arterial inertance as the fourth element of the windkessel model. Am J Physiol. 1999;276:H81–H88(Heart Circ Physiol 45)
  27. Nosè Y. The fluid-amplifier artificial heart. In:  Levine SN editors. Advances in biomedical engineering and medical physics—cardiac engineering. vol. 3:Interscience Publishers; 1970;
  28. Miroslav K. Comparative testing of artificial hearts and heart valves in mock circulation. In:  Levine SN editors. Advances in biomedical engineering and medical physics—cardiac engineering. vol. 3:Interscience Publishers; 1970;
  29. Pierce WS, Landis T, O’Bannon W, Donachy JH, White W, Phillips WM, et al. Automatic control of the artificial heart. Trans Am Soc Artif Int Organs. 1976;22:347–356
  30. Hennig E, Mohnhaupt A, Bucherl ES. The influence of filling pressure on the output of pneumatically driven blood pumps. Proc Eur Soc Artif Organs. 1976;3:19–22
  31. Arabia M, Guerrisi M, Magrini A, Tanski T. Control of the total artificial heart, in Elettromedicali. 1985; 87–110.
  32. Spinelli JC, Valentinuzzi ME, Clavin OE, Cabrera Fischer EL, Pichel RH. Stability and repeatability of the multielectrode admittancimetric intraventricular volume measurements. Automedica. 1988;11(4):343–356
  33. Valentinuzzi ME, Spinelli JC. Intracardiac measurements with the impedance technique. IEEE Eng Med Biol Mag. 1989;8(1):27–34
  34. Herrera MC, Olivera JM, Martinez RJ, Estela R, Valentinuzzi ME. Influence of surrounding structures on parallel volume determinations by conductance catheter. Cardiovasc Eng. 2001;1(3):117–125
  35. Unger F, Deutsch M, Losert U, Polzer K, Stellway F, Thoma H, et al. The ellipsoid heart as a design for total artificial heart replacement and left ventricular assist device (E-LVAD) driven by an automatic driving system. Artif Organs. 1978;(Suppl. 2):[Proceedings of the first ISAO meeting, vol. 2, p. 200]
  36. Mohnhaupt A, OH KT, Kless H, Bucherl ES. Automatic control of the artificial heart. Artif Organs. 1977;1:137–142
  37. Kwan-Gett CS, Wu Y, Collan R, Jacobsen S, Kolff WJ. Total replacement artificial heart and driving system with regulation of cardiac output. Trans Am Soc Artif Int Organs. 1969;15:245–250
  38. Harasaki H, Takatami S, Suwa S, Jacobs G, Snow J, Kiroly R, et al. Hemodynamic regulation in total artificial heart recipients. Artif Organs. 1981;5:38–45
  39. Pierce WS, Landis DL, O’Bannon W, Donachy JH, White W, Phillips WM, et al. Automatic control of the artificial heart. Trans Am Soc Artif Int Organs. 1976;22:347–356
  40. Konishi H, Misawa Y, Fuse K, Sohara Y. Pitfalls in the development of rotary blood pumps. ASAIO J. 2001;47(4):397–400

PII: S1350-4533(06)00187-1

doi: 10.1016/j.medengphy.2006.09.004

Medical Engineering & Physics
Volume 29, Issue 8 , Pages 829-839 , October 2007