Medical Engineering & Physics
Volume 29, Issue 3 , Pages 367-374 , April 2007

Hardware-in-the-loop-simulation of the cardiovascular system, with assist device testing application

  • B.M. Hanson

      Affiliations

    • School of Mechanical Engineering, University of Leeds, Leeds LS2 9JT, UK
    • Corresponding Author InformationCorrespondence to: Department of Mechanical Engineering, University College London, Torrington Place, London WC1E 7JE, UK. Tel.: +44 7879 415 504.
  • ,
  • M.C. Levesley

      Affiliations

    • School of Mechanical Engineering, University of Leeds, Leeds LS2 9JT, UK
  • ,
  • K. Watterson

      Affiliations

    • Yorkshire Heart Centre, Leeds General Infirmary, Leeds, UK
  • ,
  • P.G. Walker

      Affiliations

    • School of Mechanical Engineering, University of Leeds, Leeds LS2 9JT, UK

Received 29 November 2005 ,Revised 13 March 2006 ,Accepted 9 May 2006.

References 

  1. Oz MC, Artrip JH, Burkhoff D. Direct cardiac compression devices. J Heart Lung Transplant. 2002;21(10):1049–1055
  2. Macnair R, Underwood MJ, Angelini GD. Biomaterials and cardiovascular devices. Proc Inst Mech Eng. 1998;212(Part II):465–471
  3. Wu Y, Allaire P, Tao G, Wood H, Olsen D, Tribble C. An advanced physiological controller design for a left ventricular assist device to prevent left ventricular collapse. Artif Organs. 2003;27:926–930
  4. Ferrari G, Kozarski M, De Lazzari C, Gorczynska K, Mimmo R, Guaragno M, et al. Modelling of cardiovascular system: development of a hybrid (numerical-physical) model. Int J Artif Organs. 2003;26(12):1104–1114
  5. Urbaszek A, Schaldach M. A numerical heart and circulation model to simulate hemodynamics for rate-responsive pacing. In:  Power H editors. Bio-fluid mechanics. Southampton/Boston: Computational Mechanics Publications; 1995;p. 129–160
  6. Pillon M, Duffour H, Jufer M. In vitro experiments: circulatory assist device interaction with a virtual cardiovascular system. In: Proceedings of Annual International Conference IEEE-EMBS, vol. 14. 1992;p. 740–741
  7. Wu Y, Allaire P, Tao G, Liu Y. In-vitro test of an adaptive flow controller for a continuous flow LVAD. In: Proceedings of American control conference. 2004;p. 1647–1648
  8. Kozarski M, Ferrari G, Clemente F, Gorczynska K, De Lazzari C, Darowski M, et al. A hybrid mock circulatory system: development and testing of an electro-hydraulic impedance simulator. Int J Artif Organs. 2003;26(1):53–63
  9. Kawaguchi O, Goto Y, Ohgoshi Y, Yaku H, Murase M, Suga H. Dynamic cardiac compression improves contractile efficiency of the heart. J Thorac Cardiovasc Surg. 1997;113(5):923–931
  10. Sunagawa K, Burkhoff D, Lim KO, Sagawa K. Impedance loading servo pump system for excised canine ventricle. Am J Physiol. 1982;243(2):H346–H350
  11. Isermann R, Schaffnit J, Sinsel S. Hardware-in-the-loop simulation for the design and testing of engine-control systems. Control Eng Pract. 1999;7:643–653
  12. Ferreira JA, Gomes Almeida F, Quintas MR, Estima de Oliveira JP. Hybrid models for hardware-in-the-loop simulation of hydraulic systems. Proc Instn Mech Engrs Part 1: J Syst Control Eng. 2004;218:465–474
  13. Hanselmann H. Hardware-in-the-loop simulation testing and its integration into a CACSD toolset. In: IEEE international symposium of computer-aided control system design. September 15–18, USA. 1996;
  14. Melchior FM, Srinivasan RS, Charles JB. Mathematical modelling of human cardiovascular system for simulation of orthostatic response. Am J Physiol (Heart Circ Physiol). 1992;262(31):1920–1933
  15. Ha R, Qian J, Wang D, Zwischenberger JB, Bidani A, Clark JW. A closed-loop model of the ovine cardiovascular system. In: Proceedings of 26th annual international conference of the IEEE EMBS. September 1–5. 2004;p. 3781–3784
  16. Olansen JB, Clark JW, Khoury D, Ghorbel F, Bidani A. A closed-loop model of the canine cardiovascular system that includes ventricular interaction. Comput Biomed Res. 2000;33:260–295
  17. Hanson BM, Levesley MC, Watterson K, Walker PG. Simulation of the human cardiovascular system for real-time interaction with an assist device. In: Proceedings of 27th annual international conference of the IEEE EMBS, (EMBC ’05). September 1–4, Shanghai, China. 2005;
  18. Hanson BM, Richardson RC, Davies GLJ, Watterson K, Levesley MC, Walker PG. Control of a non-blood contacting cardiac assist device. In: Proceedings of IASTED international conference on biomedical engineering BioMED2005. February 16–18. 2005;p. 679–684

PII: S1350-4533(06)00105-6

doi: 10.1016/j.medengphy.2006.05.010

Medical Engineering & Physics
Volume 29, Issue 3 , Pages 367-374 , April 2007