Medical Engineering & Physics
Volume 28, Issue 5 , Pages 455-459, June 2006

The constitutive properties of the brain paraenchyma:

Part 2. Fractional derivative approach

Department of Applied Mathematics, University of Waterloo, Waterloo, Ont., Canada N2L 3G1

Received 19 July 2004; received in revised form 10 January 2005; accepted 15 July 2005. published online 27 October 2005.

Abstract 

Fractional models have proven to be very useful for studying viscoelastic materials. We consider the fractional Zener model (also called four-parameter model) to study both the relaxation function and creep compliance. The analytical results are compared with the known experimental results of the human brain tissue to obtain the best fit and brain mechanical parameters. The results are also compared to the non-fractional Zener model and four-parameter Burgers model, indicating that the four-parameter fractional model gives a substantially better fit for the all experimental data.

Keywords: Brain biomechanics, Viscoelasticity, Fractional derivative, Mathematical modeling

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PII: S1350-4533(05)00185-2

doi:10.1016/j.medengphy.2005.07.023

Medical Engineering & Physics
Volume 28, Issue 5 , Pages 455-459, June 2006